Record Production Capabilities Strengthen sanofi pasteur’s Global
Leadership in the Fight Against Seasonal Influenza and Place
the Company at the Forefront of Pandemic Readiness
sanofi pasteur, the vaccines business of the sanofi-aventis Group (NYSE:
SNY; EURONEXT: SAN), announced that it completed production of more than 170
million doses of influenza vaccine in 2006.
sanofi pasteur confirmed its leadership as one of the world’s largest
manufacturers of seasonal influenza vaccine, supplying a very significant
portion of the estimated global production of about 350 million doses(1).
As the global influenza vaccine leader, sanofi pasteur has been steadily
increasing its manufacturing capacity. Since 2003, capacity has increased by
more than 40% in line with the company’s commitment to serve a central role in
the fight against a disease that causes between three and five million cases of
severe illness and between 300,000 and 500,000 estimated deaths every year
around the world according to the Word Health Organization(1).
In addition, sanofi pasteur’s leadership position in developing and
producing influenza vaccines places the company at the forefront of readiness
against the threat of pandemic influenza. The company is committed to producing
as many doses of sanofi pasteur’s most advanced vaccine in the shortest
possible timeframe, should a pandemic be declared by the world’s health
authorities.
“By producing a record number of doses of seasonal influenza vaccine in
2006, sanofi pasteur demonstrates once again its steadfast commitment to fight
a serious disease that affects the lives of millions of individuals each year
and heavily weighs upon public health systems everywhere,” said Jean-François
Dehecq, Chairman and CEO of sanofi-aventis. “sanofi pasteur’s strong industrial
capabilities combined with a high-priority pandemic influenza vaccine research
program involving over 100 of our top scientists is enabling us to provide a
meaningful contribution to global pandemic preparedness,” added Mr. Dehecq.
Since 1995, sales volume of sanofi pasteur’s influenza virus vaccines has
more than tripled. To keep pace with the world’s growing immunisation needs,
sanofi pasteur has made significant capital investments in influenza vaccine
production capabilities in the United States and France in order to reach
current levels of more than 170 million doses.
In 2005, sanofi pasteur initiated a USD 160 million investment in the
United States for a new influenza vaccine manufacturing facility, which is
anticipated to double its US production capacity. New production capacities are
planned to come online for the 2008/9 influenza season. A EUR160 million
investment, the largest capital investment to date for sanofi pasteur in
France, has also been approved for a formulation and filling facility in sanofi
pasteur’s Val de Reuil facility. The new state-of-the-industry facility will
boost sanofi pasteur filling capabilities, thus significantly reducing time to
market for the vaccine.
Seasonal Influenza Overview
Influenza is a highly infectious virus that spreads easily from person to
person, primarily when an infected individual coughs or sneezes. According to
the World Health Organization (WHO), 5-15% of the population is affected with
upper respiratory tract infections in annual influenza epidemics.
Hospitalisation and deaths mainly occur in high-risk groups (elderly,
chronically ill (people with chronic conditions/illness). Although difficult to
assess, these annual epidemics are thought to result in between three and five
million cases of severe illness and between 300 000 and 500 000 deaths every
year around the world(1). Most deaths currently associated with influenza in
industrialised countries occur among the elderly over 65 years of age.
Pandemic Influenza Overview
Influenza is a disease caused by a highly infectious virus that spreads
easily from person to person, primarily when an infected individual coughs or
sneezes. An influenza pandemic is a global epidemic of an especially virulent
virus, newly infectious for humans, and for which there is no pre-existing
immunity. This is why these pandemic strains have such potential to cause
severe morbidity and mortality. According to the World Health Organization
(WHO), the next pandemic is likely to result in 1 to 2.3 million
hospitalisations and 280,000 to 650,000 deaths in industrialized nations alone.
Its impact is expected to be even more devastating in developing countries. In
an attempt to minimise the impact of a pandemic, many countries are developing
national and transnational plans against an eventual influenza pandemic
situation.
For information about sanofi pasteur pandemic preparedness program, please
visit: www.sanofipasteur.com/pandemicpreparedness
About sanofi-aventis
The sanofi-aventis Group is the world’s third-largest pharmaceutical
company, ranking number one in Europe. Backed by a world-class R&D
organisation, sanofi-aventis is developing leading positions in seven major
therapeutic areas: cardiovascular disease, thrombosis, oncology, metabolic
diseases, central nervous system, internal medicine, and vaccines. The
sanofi-aventis Group is listed in Paris (EURONEXT: SAN) and in New York (NYSE:
SNY). For more information, please visit: www.sanofi-aventis.com
sanofi pasteur, the vaccines business of the sanofi-aventis Group, sold
more than a billion doses of vaccine in 2005, making it possible to protect
more than 500 million people across the globe. The company offers the broadest
range of vaccines, providing protection against 20 bacterial and viral
diseases. For more information, please visit: www.sanofipasteur.com
Reference: 1. www.who.int/vaccine_research/diseases/ari/en/print.html